1pBB11. Ultrasonic reflection imaging with a heterogeneous background for breast cancer detection and diagnosis.

Session: Tuesday Afternoon, Nov 28


Author: Lianjie Huang
Location: Los Alamos Natl. Lab., M.S. D443, Los Alamos, NM 87545
Author: Youli Quan
Location: Stanford Univ., Stanford, CA 94305
Author: Nebojsa Duric
Location: Karmanos Cancer Inst., Detroit, MI 48201
Author: Cuiping Li
Location: Karmanos Cancer Inst., Detroit, MI 48201

Abstract:

Sound speeds and densities of breast tissue vary in space, and those of tumors are different from the surrounding tissues. These differences in mechanical properties cause scattering of ultrasonic waves, particularly in dense breasts. An ultrasonic reflection imaging method using a heterogeneous background is presented to properly account for scattering off heterogeneities within the breast. The method is based on downward continuation of ultrasonic wave fields in the frequency-space and frequency-wave-number domains. Synthetic ultrasonic data for scatterers within a heterogeneous breast model were used to investigate the imaging resolution of the method. Imaging examples using ultrasonic data acquired using a clinical prototype, consisting of an ultrasound scanner with a ring transducer array, are presented. The heterogeneous background sound-speed models were obtained using transmission tomography. The imaging results are compared with those obtained using a homogeneous background. The study demonstrates that imaging with heterogeneous backgrounds significantly improves image quality and resolution. [This work was supported through the DOE Laboratory-Directed Research and Development program at Los Alamos National Laboratory.]